The Two Cultures

Studies on the replication of African Horse Sickness Virus in two different cell line cultures

Stereospecific Biotransformation of (±) Phenylethyl Propionate by Cell Cultures of Peganum harmala L.

The enzymatic potential of the cultured plant cells can be employed for bioconversion purposes. Plant enzymes are able to catalyze regio- and stereo-specific reactions, and therefore can be applied for the production of desired substances. The biotransformation of foreign substrates with suspension cells of Peganum harmala was tested with (±) phenylethyl propionate. The callus cultures of Pegan...

A Wicked Problem? Whistleblowing in Healthcare Organisations; Comment on “Cultures of Silence And Cultures of Voice: The Role of Whistleblowing in Healthcare Organisations”

Mannion and Davies’ article recognises whistleblowing as an important means of identifying quality and safety issues in healthcare organisations. While ‘voice’ is a useful lens through which to examine whistleblowing, it also obscures a shifting pattern of uncertain ‘truths.’ By contextualising cultures which support or impede whislteblowing at an organisational level, two issues are overlooked...

Whistleblowing: Don’t Encourage It, Prevent It; Comment on “Cultures of Silence And Cultures of Voice: The Role Of Whistleblowing in Healthcare Organisations”

In a recent article, Mannion and Davies argue that there are a multitude of ways in which organizations (such as the National Health Service [NHS]) can deal with wrongdoing or ethical problems, including the formation of policies that encourage and protect would-be whistleblowers. However, it is important to distinguish internal reporting about wrongdoing from whistleblowing proper, because the...

BIO treatment enhances rat marrow-derived mesenchymal stem cell in vitro proliferation and viability

Introduction: Previous investigations have indicated that the presence of BIO (6-Bromoindirubin-3-Oxime) in medium of some cell culture enhances the cell proliferation and viability. The aim of the present study was to investigate the BIO effects on in vitro expansion of rat marrow-derived mesenchymal stem cells (MSCs) culture. Methods: In the present experimental study, bone marrow cells from ...

Bridging the ‘Two Cultures’ of Research and Service: Can Complexity Theory Help?; Comment on “Experience of Health Leadership in Partnering With University-Based Researchers in Canada – A Call to ‘Re-imagine’ Research”

This commentary addresses Bowen et al’s empirical study of perspectives of Canadian healthcare staff towards research and their call for multi-faceted action to improve misalignments in the system. This commentary argues that tensions and misalignments between research and service are inherent and can never be eradicated. Building on previous work by Lanham et al, I pro...